The TIBC test measures the blood’s capacity to bind iron, providing insight into iron metabolism. Elevated TIBC levels can suggest iron deficiency anemia, with symptoms including fatigue, weakness, and pallor. Reduced TIBC levels may indicate anemia of chronic disease or iron overload conditions like hemochromatosis, with symptoms related to chronic illness or excess iron storage. This test is essential for diagnosing and managing anemia and evaluating iron status.