The Lp-PLA2 test evaluates cardiovascular risk by measuring inflammation associated with atherosclerosis. Elevated Lp-PLA2 levels can indicate an increased risk of developing heart disease or stroke, as this enzyme is involved in the inflammation and formation of arterial plaques. Symptoms related to high Lp-PLA2 levels may include chest pain or other symptoms of cardiovascular disease. The test helps in assessing overall cardiovascular health, guiding preventive measures, and monitoring the risk of heart-related events.