The Estradiol (E2) test helps diagnose and monitor conditions related to abnormal estrogen levels. Elevated estradiol levels can be linked to symptoms such as heavy menstrual bleeding, ovarian tumors, or estrogen dominance, while low levels may indicate menopause, premature ovarian failure, or hormonal imbalances. This test is useful for evaluating reproductive health, diagnosing menstrual disorders, and guiding hormone replacement therapy or other treatments related to estrogen balance.