Celiac Disease DNA Testing can evaluate genetic risk for developing the condition. It is estimated that Celiac Disease affects approximately 1 in 100 Caucasians, with a higher occurrence in females at a two-to-one ratio. Additionally, gluten intolerance is more common in high-risk groups, including first-degree relatives of patients and individuals with certain genetic syndromes (such as Down, Turner, and Williams) or autoimmune conditions (like type 1 diabetes, thyroiditis, and multiple sclerosis).